What is new in the landscape of insulin-sensitizing agents for polycystic ovary syndrome treatment

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Effects of insulin-sensitizing agents and insulin resistance in women with polycystic ovary syndrome

OBJECTIVE The aim of this study was to investigate the effect of insulin sensitizing agents on hormonal and metabolic parameters as well as menstrual patterns in women with polycystic ovary syndrome (PCOS). METHODS One hundred and twenty-three patients with PCOS were included. Metformin was administered to patients at 1,500 mg or 1,700 mg daily for 3 months. If the patients had no improvement...

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Insulin-sensitising agents in polycystic-ovary syndrome.

Insulin-sensitizing agents have been recently proposed as the therapy of choice for polycystic ovary syndrome (PCOS), since insulin resistance and associated hyperinsulinemia are recognized as important pathogenetic factors of the syndrome. Moreover, since almost all obese PCOS women and more than half of those of normal weight are insulin resistant, and therefore present some degree of hyperin...

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Insulin-sensitizing agents: use in pregnancy and as therapy in polycystic ovary syndrome.

Treatment with insulin-sensitizing agents is a relatively recent therapeutic strategy in women with polycystic ovary syndrome (PCOS) and insulin resistance. The key areas addressed in this review include PCOS and the development of type 2 diabetes mellitus and gestational diabetes, as well as the use of insulin-sensitizing agents, particularly metformin, in the management of infertility in obes...

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Herbal Medicine in the Treatment of Polycystic Ovary Syndrome

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder that affects between 5 - 10% of women who are of reproductive age. The most common symptoms of PCOS are obesity/difficulty losing weight, acne, amenorrhea (absence of menstrual cycles), irregular menstrual cycles, hirsutism (increased growth of corporal hair), insulin resistance, and high cholesterol. One of the treatments for PCOS is the ...

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High Serum Ferritin Concentrations in Polycystic Ovary Syndrome Is Not Related to Insulin Resistance

OBJECTIVE: Some data are available on the association between components of the insulin resistance syndrome and serum ferritin. Insulin resistance is observed in patients with polycystic ovary syndrome (PCOS) We hypothesize that body iron stores might be increased in these women. MATERIALS AND METHODS: Two hundred and six people (103 PCOS patients and 103 healthy women who were matched for a...

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ژورنال

عنوان ژورنال: Therapeutic Advances in Reproductive Health

سال: 2020

ISSN: 2633-4941,2633-4941

DOI: 10.1177/2633494120908709